Development
| 1886 | Founder Chubei Kobayashi established Kobayashi Seidaido, an unlimited partnership company, in Monzen-cho, Naka-ku, Nagoya The Company sold general merchandise, cosmetics |
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| 1894 | Launched 10 types of proprietary pharmaceuticals including Daikokumaru, Ichinichimaru and Tamushichinki |
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| 1912 | Established Kobayashi Daiyakubou, a limited partnership company, in Hiranomachi, Higashi-ku, Osaka | |
| 1919 | Incorporated as Kobayashi Daiyakubou Co., Ltd. in Kyomachibori, Nishi-ku, Osaka through a merger involving unlimited partnership company Kobayashi Seidaido and limited partnership company Kobayashi Daiyakubou | |
| Kichitaro Kobayashi is appointed as the first president | ||
| 1939 | Launched Hakkiri, a headache medicine | |
| 1940 | Spun off the manufacturing unit of Kobayashi Daiyakubo, to establish Kobayashi Pharmaceutical Co., Ltd. | |
| Juso Plant began operations in Higashi-yodogawa-ku, Osaka (currently Yodogawa-ku) | ||
| 1948 | Saburo Kobayashi is appointed as the second president | |
| 1956 | Kobayashi Daiyakubou Co., Ltd. and Kobayashi Pharmaceutical Co., Ltd. were merged and renamed Kobayashi Pharmaceutical Co., Ltd. | |
| Relocated the Head Office to Dosho-machi, Higashi-ku, Osaka (currently Dosho-machi, Chuo-ku) | ||
| 1958 | Teruko Kobayashi is appointed as the third president | |
| 1966 | Launched Ammeltz, an external anti-inflammatory,as trial sales |  |
| 1967 | Launched Ammeltz, an external anti-inflammatory,as nationwide sales | |
| 1969 | Launched Bluelet, a toilet bowl cleaner, and entered the household products market |  |
| 1972 | Formed partnership with C.R. Bard, Inc. of the U.S. to establish medical devices importer-Japan Medico, Inc. and enter the medical devices market | |
| 1975 | Launched Sawaday, a toilet air freshener, and entered the deodorizing air fresheners market |  |
| 1976 | Kazumasa Kobayashi is appointed as the fourth president | |
| Japan Medico, Inc. became Medicon, Inc., a joint venture company with C.R. Bard, Inc. | ||
| 1983 | Established Toyama Kobayashi Pharmaceutical Co., Ltd. (Toyama City, Toyama Prefecture) | |
| 1988 | Angel Ltd. made a consolidated subsidiary of Kobayashi Pharmaceutical Co., Ltd. to gain a manufacturing site (Niihama City, Ehime Prefecture) | |
| 1992 | Established Kobayashi Medical, as part of the Medical Devices Business | |
| 1993 | Established Sendai Kobayashi Pharmaceutical Co., Ltd. (Kurokawa-gun, Miyagi Prefecture) | |
| 1996 | Launched Toughdent, denture cleanser | |
| 1998 | Established Shanghai Kobaysahi Friendship Daily Chemicals Co., Ltd., a joint venture company in China | |
| Established Kobayashi Healthcare, Inc. in the U.S. | ||
| 1999 | Listed on the Second Section of the Osaka Securities Exchange | |
| Launched nutritional supplements through the mail order sales channel | ||
| 2000 | Listed on the First Section of the Tokyo Stock Exchange and Osaka Securities Exchange | |
| Established the Central R&D Laboratory in Ibaraki City, Osaka Prefecture | ||
| Spun-off the Trade Company to form Kobashou Co., Ltd. | ||
| 2001 | Acquired Kiribai Chemical Co., Ltd. a body warmer manufacturer, as a subsidiary (Yodogawa-ku, Osaka) | |
| Established Kobayashi Healthcare Europe, Ltd. in the United Kingdom | ||
| 2002 | Established Kobayashi Pharmaceutical (Hong Kong) Co., Ltd. in Hong Kong | |
| Made Shanghai Kobayashi Friendship Daily Chemicals Co., Ltd. into a wholly owned subsidiary and changed its name to Shanghai Kobayashi Daily Chemicals Co., Ltd. | ||
| Took over the health food business, mainly for Tochucha (Eucommia leaf tea), from Hitachi Zosen Corporation | ||
| 2003 | Angel Ltd. renamed Ehime Kobayashi Pharmaceutical Co., Ltd. | |
| 2004 | Yutaka Kobayashi was appointed as the fifth president. | |
| 2005 | Obtained exclusive distribution rights for women's health medicine Inochi No Haha A from Sasaokayakuhin Corporation | |
| 2006 | Made eVent Medical Ltd., a medical device manufacturer, into a subsidiary in Ireland | |
| Made HeatMax Inc., a body warmer manufacturer in the U.S., into a subsidiary | ||
| 2008 | Kobasho Co., Ltd. and Mediceo Paltac Holdings Co., Ltd. conducted share exchange | |
| Spun off the manufacturing division of Kiribai Chemical Co., Ltd. to establish Kiribai Kobayashi Pharmaceutical Co., Ltd. | ||
| Obtained trademark right for Bisrat Gold from Ishihara Chemical Co., Ltd. | ||
| 2009 | Established Kobayshi Pharmaceutical (Singapore) Pte. Ltd. in Singapore | |
| 2010 | Spun off medical device division into Kobayashi Medical Co., Ltd. | |
| 2011 | Transferred all eVent Medical INC. shares in a management buy-out | |
| Established Kobayashi Healthcare (Malaysia) Sdn. Bhd. in Malaysia | ||
| Established Kobayashi Pharmaceutical (Taiwan) Co., Ltd. in Taiwan | ||
| 2012 | Made Grabber, Inc., a body warmer manufacturer in the U.S., a subsidiary | |
| Established PT. Kobayashi Pharmaceutical Indonesia in Indonesia | ||
| Established Hefei Kobayashi Daily Products Co., Ltd. in China | ||
| Transferred 80% of Kobayashi Medical Co., Ltd. shares to Mitsubishi Corporation | ||
| 2013 | Made Rokuyo Pharmaceutical Co., Ltd., a pharmaceutical product, quasi-pharmaceutical product, and cosmetics manufacturer, into a subsidiary | |
| Established Kobayashi Healthcare Australia Pty., Ltd. in Australia | ||
| Transferred all Japan Medicalnext Co., Ltd. shares to Mitsubishi Corporation | ||
| Akihiro Kobayashi is appointed as the sixth president | ||
| Established Kobayashi Healthcare (Thailand) Co., Ltd. in Thailand | ||
| Made Juju Cosmetics Co., Ltd., a cosmetics manufacturer, into a subsidiary | ||
| 2015 | Acquired Ganyaku Hitifuku brand from Hitifuku Pharmaceuticals Co., Ltd. | |
| Dissolved its joint venture with U.S. company Bard International Inc. and sold all its shares to Medicon, Inc. |
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| 2016 | Acquired monascus purpureus business from GUNZE LIMITED | |
| Made perfecta products, Inc., a U.S. company involved in the planning and sales of OTC pharmaceuticals and cosmetics, into a subsidiary | ||
| 2017 | Acquired exclusive marketing rights in Japan for Bioil from Union Swiss(Pty) Ltd (headquartered in South Africa) | |
| Established The Kobayashi Foundation | ||
| 2018 | Established Kobayashi (China) Co., Ltd in China | |
| Acquired Jiangsu Zhongdan pharmaceutical Co,. Ltd, a pharmaceutical products manufacturer, and changed the company name to Jiangsu Kobayashi pharmaceutical Co,. Ltd. | ||
| 2019 | Made Meitanhompo Co.,Ltd., a health foods manufacturer, into a subsidiary | |
| 2020 | Made Alva-Amco Pharmacal Companies, Inc., a U.S. company involved in a pharmaceutical products manufacturer, into a subsidiary | |
